FACTORS AFFECTING WOUND HEALING
1. Tissue perfusion and oxygenation
2. Nutritional status
3. Infection
4. Systemic states affecting wound healing
5. Corticosteroid administration
6. Immunosuppression
7. Aging
8. Systemic factors
9. Topical Therapy
1. Tissue perfusion and oxygenation
Oxygen is essential for the repair process in damaged cells in the body.
Sufficient amount of oxygen in the body can accelerate the healing process.
If there Hypoxia can lead to healing the wounds become longer, because:
Impaired Collagen Synthesis,
Decreased epithelial proliferation and migration,
Reduced tissue resistance to infection.
2. Nutritional status
Nutritional status is very important for the body. Nutrient content is needed by
the body to repair damage to cells and infection prevention.
Nutritional status is very helpful, such as wound healing process:
Adequat Protein.
Calories.
Vitamin C.
Vitamin A.
B Complex vitamins
Iron.
Copper.
Zinc.
3. Infection
The process of infection can cause wound healing becomes long, as happened a long
period of inflammation and cell damage on the necessary treatment for the
infection.
To determine the existence of bacteria in the infection process of examination
and examination of the wound tissue culture or culture techniques.
Wound Culture and Sensitivity:
Sign of local infection.
Sign of systemic infection.
Bone involvement.
Non healing wound.
If Accurate culture;
obtain appropriate cultures.
Use correct technique to minimize risk of contamination.
4. Diabetes Mellitus Reduced collagen synthesis.
Impaired wound contraction
Delayed epidermal migration.
5. Corticosteroid Administration
Inhibit Epithelial proliferation
Anti inflammatory effects.
6. Immunosuppression
Disease processes and treatments that suppress the immune system can cause delay
wound healing process.
7. Aging
Aging process changes on the skin and the skin layer. The skin can be damaged and
less ability the healing process.
8. Systemic factors
Renal and Hepatic disease.
Malignancy and Sepsis.
Hemapoetic abnormal.
9. Topical Therapy
Topical treatment is helpful in the process of wound healing.